Detection of rare mutant cancer cells in a background of extremely abundant wild-type cells.
SuperSelective primers, by virtue of their unique design, employ thermodynamic and kinetic principles that enable the routine quantitation of as few as 10 mutant molecules in samples containing 1,000,000 wild-type molecules, even if the mutation is only a single-nucleotide polymorphism. The early detection of relevant somatic mutations has multiple uses, including:
Additional information on SuperSelective primers:
A smartphone-based DNA & RNA detection platform – no lab necessary
Biomeme makes a mobile, field-based platform for performing real-time PCR, RT-PCR, and isothermal molecular analysis. The one3™ thermocycler runs up to six tests on a single battery charge, weighs only 1.2 pounds, and can sync all results with a web portal that can be accessed remotely for real-time monitoring of test results and further analysis. While the one3™ is highly configurable and easy to port assays onto, Biomeme also offers fully optimized field kits serving the human health, biothreat, and environmental markets.